I love board games and get so excited to find fun yet educational games for the whole family. They have party games, engaging games, young player games. A game for everyone! Put away the video games and get out a great board game for the whole family.
I loved the idea of learning geography through a board game so I chose 10 Days in the Americas for my review game.?
2 of my boys played the first round alone, it was fun to watch them search for the route they needed to take to make their trip complete. The object of the game is to create a 10 day trip where each country is assessable to the one beside it on the individual's tray. The countries can either be next to each other or you would need to travel on a boat or airplane. By trading and exchanging cards you develop your 10 day trip in hops of being the first one done.?
I joined in with them for the next game. Sounded like it would be a piece of cake.. wrong! Just when you think you have a good sequence going you have to switch things around to get to the country at the end of your tray. It was great fun while I played with my 3 teen boys. I didn't win but I sure had fun trying! There were countries in the game I had never heard of and had to locate. Perfect for learning about new countries! I love that there are other 10 days games from Out of the Box, Africa, Europe, Asia and even the USA. A super fun way to learn geography as well as planning and thinking ahead in a game. Definitely takes some skill in decision making, ages 10 to adult.?
The game takes roughly 30 minutes to play, so not as involved as some all day long games. Super for a game night with the family or the middle of the homeschool day.?
You will be able to enter to win this game during the Luck of Liberty Blog Hop beginning July 2nd!
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Out of the Box Games Facebook? @otbgames
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Disclosure: The reviews and or opinions on this blog are my own opinions. I received the above to review. No monitory compensation was received. I was not required to write a positive review. Your experience may differ. The opinions I have expressed are my own I am disclosing this in accordance with the Federal Trade Commissions 16 CFR Part 255: Guides Concerning the Use of Endorsement and Testimonials in Advertising.
Chicago is home to a good successful digital marketplace, like online promotion, advertisements, flick era, web development as well as web marketing. Because from the mind-boggling want to form route within the business, Chicago Internet marketing has become a primary provider supplied throughout the majority of a digital businesses from the area. The most recent [...]
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Chicago is home to a good successful digital marketplace, like online promotion, advertisements, flick era, web development as well as web marketing. Because from the mind-boggling want to form route within the business, Chicago Internet marketing has become a primary provider supplied throughout the majority of a digital businesses from the area. The most recent and a lot necessary traits inside...
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Richard Green is a professor in the Sol Price School of Public Policy and the Marshall School of Business at the University of Southern California. This blog will feature commentary on the current state of housing, commercial real estate, mortgage finance, and urban development around the world. It may also at times have ruminations about graduate business education.
MAYOR LEE LAUNCHES U.S. MAYORS OPEN GOVERNMENT INNOVATION PARTNERSHIP
18 June 2012
Mayor Lee Joins the White House to Urge Mayors Across the Nation to Pledge
Innovation-Led Drive for Job Growth, Improved Government Efficiency & Greater Collaboration
Today, Mayor Edwin M. Lee, as Chair of the first U.S. Conference of Mayors (USCM) Technology and Innovation Task Force, announced the Open Government Innovation Partnership ? a call to action to help cities advance and prioritize innovation to drive job growth, economic development, improved efficiency and collaboration. The USCM Technology and Innovation Task Force will be asking Mayors to join the partnership as active and committed partners to help build an ecosystem that will help cities advance and prioritize innovation to improve government.
?This is a time for cities to confront challenges by taking risks and embracing innovation,? said Mayor Lee. ?In San Francisco, we are using technology and innovation to improve city services that impact our everyday lives, from transportation to education to civic engagement.?
The USCM Open Government Innovation Partnership will: ? Strengthen and increase civic use of innovation, cross-collaboration and improved accountability through open government initiatives; ? Showcase the leadership of cities highlighting innovation and creative best practices to increase opportunities for collaboration with the private sector; ? Secure commitments that will make city governments more efficient, effective, and responsive by embracing the use of open government innovation; and ? Empower private sector organizations to partner with government to make services more efficient, effective, and responsive to residents.
The action plans promote transparency, support a marketplace for entrepreneurship, energize civic engagement and collaboration, and leverage new technologies.
Last week, Mayor Lee hosted a forum recognizing the critical role that technology and innovation play in cities by sharing best practices to enable innovation at the 80th Annual Meeting of the U.S. Conference of Mayors in Orlando, Florida. The forum included former White House Chief Technology Officer Aneesh Chopra, White House Deputy Chief Technology Officer and former San Francisco Chief Information Officer Chris Vein and Code for America Executive Director Jen Pahlka.
The USCM Technology and Innovation Task Force also passed a resolution to support open government and the release of data at all levels of government to spur entrepreneurship, foster economic growth and create jobs. The mayors resolved to work closely with Congress and the Obama Administration to expand funding to support initiatives that direct resources to harness the capability of local economies nationwide in developing regional industry, innovation and export clusters.
Genetic markers hope for new brain tumor treatmentsPublic release date: 15-Jun-2012 [ | E-mail | Share ]
Contact: Emma Thorne emma.thorne@nottingham.ac.uk 44-011-595-15793 University of Nottingham
Researchers at The University of Nottingham have identified three sets of genetic markers that could potentially pave the way for new diagnostic tools for a deadly type of brain tumour that mainly targets children.
The study, published in the latest edition of the prestigious journal 'Lancet Oncology, was led by Professor Richard Grundy at the University's Children's Brain Tumour Research Centre and Dr Suzanne Miller, a post doctoral research fellow in the Centre.
It focuses on a rare and aggressive cancer called Central Nervous System primitive neuro-ectodermal brain tumours. Patients with CNS PNET have a very poor prognosis and current treatments, including high dose chemotherapy and cranio-spinal radiotherapy are relatively unsuccessful and have severe lifelong side-effects. This is particularly the case in very young children.
Despite the need for new and more effective treatments, little research has been done to examine the underlying causes of CNS PNET, partly due to their rarity. The Nottingham study aimed to identify molecular markers as a first step to improving the treatments and therapies available to fight the cancer.
The Nottingham team collaborated with researchers at the Hospital for Sick Kids in Toronto, Canada, to perform an International study collecting 142 CNS PNET samples from 20 institutions in nine countries.
Professor Richard Grundy said: "Following our earlier research we realised that an international effort was needed to bring sufficient numbers of cases together to make the breakthrough we needed to better understand this disease or indeed diseases identified in our study. The next step is to translate this knowledge into improving treatments."
By studying the genetics of the tumours, they discovered that instead of one cancer, the tumours have three sub-types featuring distinct genetic abnormalities and leading to different outcomes for patients.
They found that each group had its own genetic signature through subtle differences in the way they expressed two genetic markers, LIN28 and OLIG2.
When compared with clinical factors including age, survival and metastases (the spread of the tumours through the body), they discovered that group 1 tumours (primitive neural) were found most often in the youngest patients and had the poorest survival rates. Patients with group 3 tumours had the highest incidence of metastases at diagnosis.
Ultimately, the research has identified the two genetic markers LIN28 and OLIG2 as a promising basis for more effective tools for diagnosing and predicting outcomes for young patients with these types of brain tumours.
The research was funded by the Canadian Institute of Health Research, the Brainchild/Sick Kids Foundation and the Samantha Dickson Brain Tumour Trust.
Chief Executive of Samantha Dickson Brain Tumour Trust, Sarah Lindsell, said: "As the UK's leading brain tumour charity, and the largest dedicated funder of brain tumour research, we are delighted that our investment has led to such significant success. It is great to see that understanding of these tumours is improving this is desperately needed given the poor outcomes for children with this tumour. Samantha Dickson Brain Tumour Trust is proud to have been instrumental in this work."
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The Children's Brain Tumour Research Centre is one of the projects set to benefit from the Impact Campaign, the biggest fundraising campaign in The University of Nottingham's 130 year history. It aims to raise 150m to transform research, enrich the student experience and enable the institution to make an even greater contribution to the global communities it serves.
The paper, Markers of Survival and Metastatic Potential in Childhood CNS Primitive Neuro-Ectodermal Brain Tumours: an Integrative Genomic Analysis, can be accessed via The Lancet's website.
[ | E-mail | Share ]
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Genetic markers hope for new brain tumor treatmentsPublic release date: 15-Jun-2012 [ | E-mail | Share ]
Contact: Emma Thorne emma.thorne@nottingham.ac.uk 44-011-595-15793 University of Nottingham
Researchers at The University of Nottingham have identified three sets of genetic markers that could potentially pave the way for new diagnostic tools for a deadly type of brain tumour that mainly targets children.
The study, published in the latest edition of the prestigious journal 'Lancet Oncology, was led by Professor Richard Grundy at the University's Children's Brain Tumour Research Centre and Dr Suzanne Miller, a post doctoral research fellow in the Centre.
It focuses on a rare and aggressive cancer called Central Nervous System primitive neuro-ectodermal brain tumours. Patients with CNS PNET have a very poor prognosis and current treatments, including high dose chemotherapy and cranio-spinal radiotherapy are relatively unsuccessful and have severe lifelong side-effects. This is particularly the case in very young children.
Despite the need for new and more effective treatments, little research has been done to examine the underlying causes of CNS PNET, partly due to their rarity. The Nottingham study aimed to identify molecular markers as a first step to improving the treatments and therapies available to fight the cancer.
The Nottingham team collaborated with researchers at the Hospital for Sick Kids in Toronto, Canada, to perform an International study collecting 142 CNS PNET samples from 20 institutions in nine countries.
Professor Richard Grundy said: "Following our earlier research we realised that an international effort was needed to bring sufficient numbers of cases together to make the breakthrough we needed to better understand this disease or indeed diseases identified in our study. The next step is to translate this knowledge into improving treatments."
By studying the genetics of the tumours, they discovered that instead of one cancer, the tumours have three sub-types featuring distinct genetic abnormalities and leading to different outcomes for patients.
They found that each group had its own genetic signature through subtle differences in the way they expressed two genetic markers, LIN28 and OLIG2.
When compared with clinical factors including age, survival and metastases (the spread of the tumours through the body), they discovered that group 1 tumours (primitive neural) were found most often in the youngest patients and had the poorest survival rates. Patients with group 3 tumours had the highest incidence of metastases at diagnosis.
Ultimately, the research has identified the two genetic markers LIN28 and OLIG2 as a promising basis for more effective tools for diagnosing and predicting outcomes for young patients with these types of brain tumours.
The research was funded by the Canadian Institute of Health Research, the Brainchild/Sick Kids Foundation and the Samantha Dickson Brain Tumour Trust.
Chief Executive of Samantha Dickson Brain Tumour Trust, Sarah Lindsell, said: "As the UK's leading brain tumour charity, and the largest dedicated funder of brain tumour research, we are delighted that our investment has led to such significant success. It is great to see that understanding of these tumours is improving this is desperately needed given the poor outcomes for children with this tumour. Samantha Dickson Brain Tumour Trust is proud to have been instrumental in this work."
###
The Children's Brain Tumour Research Centre is one of the projects set to benefit from the Impact Campaign, the biggest fundraising campaign in The University of Nottingham's 130 year history. It aims to raise 150m to transform research, enrich the student experience and enable the institution to make an even greater contribution to the global communities it serves.
The paper, Markers of Survival and Metastatic Potential in Childhood CNS Primitive Neuro-Ectodermal Brain Tumours: an Integrative Genomic Analysis, can be accessed via The Lancet's website.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Holidays such as Memorial Day, 4th of July, Labor Day, or any picnic holiday can cause break downs in our otherwise healthy eating plan.? It is extremely important to be very aware that picnics can pack literally thousands of calories that we would not normally indulge in.? So, what should you do?
1.? Continue to practice your healthy eating habits on the picnic day.? Do not skip meals or save calories for the ?big meal?.? That sets you up to overeat!!!
2. If going to a party or picnic, offer to bring an appetizer and side dish.? That way you can guarantee there will be healthy choices for you.
3. Be watchful of your portions and choose NOT to have the desert!! Instead, maybe bring a box of sugar free popcycles to share with the crowd or have a cup of coffee instead!.
4. Make sure that you do not slack off from your daily exercise routine the day of the picnic. ?Try adding 10 or 15-minute brisk walks twice that day with available family members or the partygoers. Plan active activities such as crochet, bike riding, or taking a hike instead of sitting around and talking or watching TV.
5. If you are throwing the party, have lots of vegetables available, and instead of chips, choose a low carb low sugar variety of snack such as Medifast Puffs or Pretzels. Prepare lower fat dips and offer salsa. Explain to your guests in advance you?re?determination to make this a healthier holiday celebration, and ask them to keep this in mind when preparing any dish they may be bringing.
6. Stay away from high calorie beverages such as sodas, juices, smoothies, and blended coffee drinks. There are nearly 150 calories in one 12-ounce can of soda or juice. Smoothies and coffee drinks are often 250-500 calories, excluding the whipped cream. Alcohol is packed full of calories and carbs. It can also cause you to let down your defenses and overeat or make poor food choices. All of these indulgences will set you back
7 I suggest to have a low glycemic protein snack before going to the cookout such as a Protein Bar or Shake. Medifast is a great low calorie, low glycemic protein meal replacement which I prefer over other meal replacements.
8. At the picnic choose healthy foods and stay away from the chips and bread and High glycemic foods such as corn.
9. If the cookout is at your house, send some of the left-overs home with your guests, especially the desserts!!
10. Remember to eat slowly, which will help you to eat less and feel full and satisfied.
11. Habits are habit forming? People form habits but habits transform people! Let?s Take Shape for Life! Let?s transform our thinking to become choosy about what we eat. Let?s make it a habit to select healthy foods and plan to integrate Medifast foods as part of our ?prescription for life?!
What does Stalker and Crysis have in common? The mod Cryzone Sector 23,?that?s?what. While it is still early days for this mod the videos they have released look fantastic. Set in the world of Stalker, the mod aims to put the Cryengine to full use recreating the game Stalker.
WoS Team were using Cryengine 2 to create ?the mod but then recently decided to move to Cryengine 3. Many mods in the past that have tried to make the shift from one engine to another have unfortunately?..disapeared, heres hoping that Cryzone sector 23will?make the move succesfully.
WoS Team recently posted an update stating that the game was shifting from Mod status to ?indie game?,
CryZone?is not a ?modification for the game Crysis?. From now is a complete,?self-Indie-game on engine CryEngine 3.
And that?s no reason to worry about losing time when moving project from one to another engine,?CryZonehave already moved to?CE3, and is actively developed, as can be judged from the?first?screenshots.
Stating that the game is 80% done, after watching the videos, one can only hope that the final 20% comes soon.
Now that all of the Harry Potter movies have been released, Warner Bros. has seen fit to slide them together in one truly epic set. Harry Potter Wizard's Collection spans 31 discs including the theatrical version of each movie, extended cuts of the first two flicks, 3D versions of the last two, Ultraviolet digital copies and several bonus discs with ten hours of new to disc bonus content and 5 hours of never before seen extras. Of course, we should also mention the incredibly detailed box it all comes in, seen in the CG video above. Of course, you can't always have everything, and some fans are upset are upset about what this collection doesn't include -- extended versions of the last six movies. Those still interested can preorder the $400 MSRP set (currently selling $349 on Amazon) for delivery September 7th, and get an early preview of one of the special features embedded after the break.
Been snacking on popcorn with the beta build of XBMC 11.0 Eden since it got released last December? If, you'll be pleased know that the full-on release version is now officially available for download. In case you don't recall, this latest build of the media center house many new features, not limited to Addon Rollbacks (in case you hate their new builds), a plethora of speed-improvements, official "in- sync support" for iOS devices, AirPlay functionality and UI tweaks. There's also good news for Ubuntu users, as XBMCUbuntu Final has been officially announced as the successor to XBMC Live. Excuse the pun, but if you're ready to taste the fruit now that it's ripe, you'll find the full details for both and the download link for Eden at the source link below.
A Presbyterian court, in a case with implications for dozens of congregations exiting a denomination divided over homosexuality, convened on Thursday to decide if a California parish may break away with property worth millions of dollars.
Testimony began before the Synod of the Pacific, consisting of ministers and church elders from throughout the West, on a case stemming from a decision by the Community Presbyterian Church of Danville, an affluent San Francisco suburb, to join a more conservative denomination.
A San Francisco-area church governing body agreed in 2010 to allow the Danville congregation to keep real estate that had been appraised at nearly $14 million after its parishioners voted to split from the mainline Presbyterian Church U.S.A.
Critics of the move, however, have argued that the regional governing body lacked authority to approve the property transfer.
"We are here today because we believe the Presbytery of San Francisco has made an unauthorized gift of property," Joan Blackstone, a retired lawyer and church elder who represents opponents of the property transfer, said in opening statements.
Thursday's trial highlights deep divisions within the parent church and its 2 million members, as well as other mainstream Protestant denominations, over the ordination of gay clergy and blessing of same-sex unions.
Although it does not allow ministers to perform same-sex marriages, the Presbyterian Church allows its ministers to bless gay unions.
The synod's trial, held in a hotel banquet room near the San Francisco Airport, will decide whether the presbytery properly used the church's so-called "gracious-dismissal" policy to allow the Danville parish to leave with its buildings and more than 7 acres of land held in trust for the Presbyterian Church U.S.A.
The committee of local ministers "considered, prayed about it and decided the buildings should continue to be used by the Danville congregation as they continue to do God's work," the Rev. Joan Huff, a San Francisco minister who represents the presbytery, told the tribunal. "Grace is not always fair. Grace cannot be monetized. It cannot be bought, earned or won."
"It if could, it would cease to be grace," she said.
Blackstone urged the 10 commissioners hearing the case to consider the impact of their decision on church groups throughout the nation struggling with how to divide property.
OPENED CLERGY TO HOMOSEXUALS
The Presbyterian Church U.S.A. formally opened the ranks of its clergy to homosexuals last spring in a move that triggered a schism, prompting some opposed to gay clergy to form a new denomination, the Evangelical Covenant Order of Presbyterians.
The Presbyterian Church's pension board further alienated some conservative congregants this month by approving benefits for same-gender partners and their children starting next year.
Upset over differences in biblical interpretation of social issues, including questions of gay life and abortion, the Danville congregation began separating from the parent church in 2010.
They want to join yet another offshoot denomination, the Evangelical Presbyterian Church. That church believes "unrepentant homosexual behavior is incompatible with the ordination vows."
"This case is going to establish a precedent of sorts in the minds of people in this denomination," Blackstone said in her opening trial statement. "It's going to be considered by congregations as they request to be dismissed."
The Kentucky-based denomination has endured other splits in its history, including schisms over slavery and the ordination of women. But the Rev. Gradye Parsons, the highest-ranking official in the church general assembly, said some congregations that have left the fold during the past 20 years have rejoined.
"I think it's sad that people are leaving," he said. "I see it more as a separation than a divorce and hope someday we can be reconciled."
The Danville church, founded in 1865, consists of about 1,800 members.
The Rev. Scott Farmer, the church's senior pastor, served on a task force charged with writing the "gracious-dismissal" policy, Blackstone said. She questioned whether Farmer had a conflict of interest when the Danville church was the first to ask to be dismissed under the policy.
Farmer could not be reached for comment.
A website for the Presbyterian Lay Committee, a conservative advocacy group, listed 35 congregations that had started the process of separating from the denomination since July. The First Presbyterian Church in Colorado Springs, with more than 4,000 members, is the largest to take part in the exodus.
The synod is expected to issue a written decision next week.
Pope Benedict XVI waves as he boards a plane on his way to a six-day visit to Mexico and Cuba, at Rome's Fiumicino international airport, on Friday
By msnbc.com news services
ABOARD THE PAPAL PLANE -- Pope Benedict said on Friday communism no longer works in Cuba and the Catholic Church was ready to help the island find new ways of moving forward without "trauma."
Speaking on the plane taking him from Rome for a trip to Mexico and Cuba, the pope told reporters: "Today it is evident that Marxist ideology in the way it was conceived no longer corresponds to reality."
Responding to a question about his visit to the island, a communist bastion 90 miles off the coast of the United States for more than 50 years, Benedict added: "New models must be found with patience and in a constructive way...we want to help."
Benedict, who is due to arrive in Cuba on Monday after a three-day visit to Mexico, called for freedom of conscience and freedom of religion on the island.
Cuba detains 70 'Ladies in White' ahead of Pope visit
Also on Friday, Benedict promised to "unmask the evil" of drug trafficking in Mexico, which has been wracked by a surge in gang violence over the past five years.
'We are all fed up' The pope gave a forceful response when asked on board his plane about drug trafficking in Mexico, which has generated violence claiming some 50,000 lives since 2007.
"We must do whatever is possible to combat this destructive evil against humanity and our youth," he told reporters. "It is the responsibility of the Church to educate consciences, to teach moral responsibility and to unmask the evil, to unmask this idolatry of money which enslaves man, to unmask the false promises, the lies, the fraud that is behind drugs."
Car bomb targets Mexico newspaper office
The relentless bloodletting was in the mind of many of those waiting to see Benedict in Leon, a Roman Catholic stronghold that has avoided the worst of the brutal turf wars between drug cartels and clashes with security forces.
"The Church has to address the violence, give us a message that there can be change. We are all fed up, our society has been hurt," said Ruben Santibanez, a local doctor.
Christophe Pierre, the Vatican's diplomatic representative in Mexico, said Benedict would not ignore Mexico's plight.
"Violence is being talked about, we can't hide it, but there is a lot more to Mexico than the violence, and the desire to live in harmony is precisely what the Holy Father is coming for," he said on Thursday.
Images: Mexico gets ready for Pope's visit
Crowds of devout Mexicans readied campsites in Leon in preparation for a massive outdoor mass on Sunday where hundreds of thousands of people are expected.
Benedict hopes to rally the faithful in the world's second most populous Catholic nation as more Mexicans are lured to evangelical Protestant churches.
But the German pope faces a challenge generating the same kind of fervor as his charismatic Polish predecessor, Pope John Paul, who was beloved in Latin America and drew pulsating crowds whenever he criss-crossed the region during his 27-year papacy.
Abuse scandals Highlighting the growing religious divisions in Mexico, a large Protestant church in Leon held a service with hundreds of worshipers on Thursday, prominently displaying a sign that read "We are not Roman Catholics."
The Vatican has been stung by accusations of child abuse by priests in parishes around the world - including revelations about Mexican religious leader Marcial Maciel, who founded a prominent Catholic order, the Legionaries of Christ.
Maciel, who died in 2008 at the age of 87, was disgraced by allegations of sexual abuse and drug addiction.
Heaven scent: Pope orders eau de cologne that he alone may wear
During the pope's visit, religious scholar Bernardo Barranco will present a new book by ex-Legionaries with scores of leaked Vatican documents the authors say prove the Holy See knew about Maciel's molestation of young boys and morphine use for decades.
The hacker group Anonymous in Mexico crashed at least two of the websites for Benedict's visit to Mexico on Thursday, claiming his trip is a political move to support the president's party.
Anonymous Mexico said in a video posted on social media sites that the pope's visit will cost Mexicans money that could be better spent on the poor, and is meant to support the PAN in the July 1 presidential election. PAN candidate Josefina Vazquez Mota trails front-runner Enrique Pena Nieto of the Institutional Revolutionary Party by at least 10 percentage points in most polls.
Reuters and The Associated Press contributed to this report.
The Islamic regime in Tehran was not satisfied with the public support the Iranian Jewish community?s was forced to confer on the Global March to Jerusalem for which Iran is recruiting Islamists worldwide. Now, the event?s organizers, Majlis Speaker Hossein Sheikh-ol-Eslam and Salim Ghafouri, have ordered the community to send a Jewish delegation to march with the Islamist groups in Lebanon, debkafile?s Iranian sources disclose.
The delegations are scheduled to mass on the Lebanese and Jordanian borders with Israel and at West Bank and Gaza checkpoints on March 30, when Israeli Arabs mark Earth Day every year.
Iran?s ancient Jewish community of around 15,000 souls (9,000 in Tehran, 4,000 in Shiraz and 1,300 in Isfahan) has been living in fear of reprisals should Israel or the United States carry out a military operation against the country?s nuclear facilities. ?Now, they face a fresh danger of murder and abduction by Hizballah and Palestinian gunmen and terrorists in Lebanon.
Jewish communal leaders were instructed by the Iranian authorities this week to have at least 10 young men aged 18 to 22 ready for the march. They were to be given ?the honor? of acting as vanguard for breaking through the Lebanese-Israeli border fence and leading a mass incursion across the border.
They suspect that this ploy is meant to prevent Israeli soldiers from firing on the trespassers for fear of killing the Jewish contingent, while at the same time, exposing them to violence when the event is over at the hands of al-Qaeda linked Palestinian groups under Hizballah protection.
The Salafi doctrine held by the al Qaeda killer Muhammad Merah who murdered four Jews, including three children, in Toulouse Monday, is rife in the south Lebanese Palestinian Ain Hilwa refugee camp. The most active are two Palestinian jihadist groups, the Abdullah Azzam Brigades, which now and then shoots rockets into northern Israel, and Jund al-Sham, which is closely tied to al Qaeda branches in Lebanon, Syria and Iraq, where they call themselves Osbat al-Ansar.
The two terrorist groups are the bosses of the Safouri Quarter of the camp.
Our sources report an Iranian scheme to send the Jewish marchers on a visit to Ain Hilwa to show their solidarity with the most radical Palestinian cause.
Last week, Jewish leaders were obliged to sign a declaration of solidarity with the Global March and condemnation of Israel. The text put before them for signing was as follows: We the Jews of Iran strongly condemn the barbaric crimes of the occupation regime in Palestinian and declare the Zionist state in violation of the principles of Our Teacher Moses and the Will of God. We are totally at one with the aspirations of the heroic Palestinian people.?
Signed: Dr. Syamak Mare Dedeq, Jewish Member of Parliament, and Rabbi Mashallah Golestani-Nejad, described as the Chief Rabbi of Iran. debkafile?s Iranian sources add: Tehran is the main bankroller and live wire of the Global March against Israel?s borders and claims to have rounded up Islamist delegations from five continents to support the Palestinians. Seventy sympathizers are on their way to Lebanon, Syria and Jordan from India, Malaysia, Pakistan and other Asian countries.
To mark the event, Tehran staged a cartoon contest. The winner drew around the Al Aqsa mosque in Jerusalem a wall modeled on the fences of Auschwitz.
Both the organizers are members of the Ministry of Intelligence MOIS with long experience?of managing Iranian activities on behalf of Arab and Palestinian terrorist groups. Sheikh-ol-Islam, while holding the post of Deputy Speaker of Parliament, also coordinates Tehran?s relations with the Lebanese Hizballah.
On Feb. 26, Supreme Leader Ayatollah Ali Khamenei proclaimed the launching of the Global March to Jerusalem an expression of Iran?s policy for strengthening ?resistance operations? against Israel and guarding Palestinian interests.
Question by DC : is precious metal investment safe and good ways to invest? what do is your opinion on investing on gold? or silver? how do you make investment on silver or gold? and what do look for before purchase? Best answer:
Answer by * Steve * Yes always is. stock. exchange #
know better? Leave your own answer in the comments!
Prostate cancer is the most common malignancy in men .Both the morbidityand mortality rate from prostate cancer rise almost exponentially in recent years.Many researches showed that its tumorgenesis and biological characters are closelyrelated to many genes. Growing evidence suggests that many kallikreins areimplicated in it. Human kallikrein gene 7(KLK7; HSCCE), also named HSCCE/PRSS6, is a new member of the human kallikrein gene family, which was found inskin first, had drawn great attention and been undertaken wide studies in manymalignant tumors.Objective The aim of this study were : (1) to determine whether KLK7 gene isexpressed in prostate cell line PC-3. (2) to investigate whether DHT had theeffects on KLK7 mRNA level in PC-3 cell in vitroMethods (1) Total RNA was extracted from human prostate cell line PC-3 andhuman kallirein7(KLK7) gene cDNA was amplified by PCR after reverse-transcription using Oligo (dT) primer. Amplified products was ligated to PGEM-TEasy plasmid vector. The recombinant plasmid was transfered to the competentE.coli DH5?. Indentified by enzyme digestion, KLK7 gene in recombinant plasmidwas sequenced by sanger dideoxy-mediated chain-termination method. (2)Thehuman prostate cell line PC-3 were cultured at 37?in a CO2 incubator with F12culture medium and were divided into seven groups by different DHT stimulatingconcentrations of 0M?10-9M?10-8M?10-7M?10-6M?10-5M and 0.01% Ethanol.Following culture in day 1, day 2, day 3 and day 4, MTT method was applied toobserve the cell proliferation . RT-PCR was engaged to find the KLK7 level in thePC-3 cell under the different concentrations of DHT stimulation.Results (1)The cloned kallikrein7 gene is about 762 bp in length. A sequencecomparison of this with the reported kallikrein7 sequence in the Genebankindicated that the cloned prostate cell line PC-3 KLK7 gene has two nucleotidedifference. (2) In day 1 of culture, the cell treated with 10-8mol/l DHT grew fast,there was significant increase of OD in this group compared with the control group( P < 0.05). In day 4 of culture , there were significant increase of OD in thegroups treated with 10-9mol/l?10-8mol/l?10-7mol/l?10-6mol/l DHT compared withthe control group ( P < 0.05) except the group treated with 10-5mol/l DHT (P >0.05). (3) RT-PCR showed that the group treated with 10-9mol/L ?10-8mol/L?10-7mol/L?10-6mol/L DHT had no KLK7 mRNA expression. TheKLK7 mRNA OD value in control group and 10-5mol/L DHT group was 0.9061?0.9367 respectively compared with control gene .Conclusion Our study indicated: (1) KLK7 gene is expressed in prostate cellline. It may be provide the evidences for further studies of the KLK7 gene inprostate cancer. (2) Lower concentration of DHT can enhance the proliferation ofPC-3 cell. Its optimal concentration is 10-8mol/L. (3) the expression of KLK7mRNA may be regulated by androgens and has certain relations with prostatecancer cell growth. Further studies are required to prove this hypothesis.
Title: Molecular Cloning of Human Prostate Cancer Cell Line KLK7 Gene and the Effects of DHT on KLK7 mRNA Level in PC-3 Cell in Vitro
Category: Malignant Tumor
Filename: Molecular Cloning of Human Prostate Cancer Cell Line KLK7 Gene and the Effects of DHT on KLK7 mRNA Level in PC-3 Cell in Vitro.pdf
Pages: 128
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Google Maps has long sported 3D models of major world landmarks. Some of them, however, left something to be desired. For example, the Piazza del Duomo in Florence was missing its signature domes. Now it's been drastically improved with a series of smooth shaded roofs. Plenty of other landmarks have also been revamped, including the Sydney Opera House, White House and the Petronas Towers. Sadly, there's word as to when or if the new models will land in the mobile version. To check them out yourself hit up the source link.
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Public release date: 19-Mar-2012 [ | E-mail | Share ]
Contact: Rob Gutro Robert.j.gutro@nasa.gov 443-858-1779 NASA/Goddard Space Flight Center
Infrared and microwave satellite imagery from NASA have been providing forecasters at the National Weather Service valuable data on weather system that has potential to bring severe weather to the south central U.S. over the next several days.
A large upper-level storm system is approaching central Oklahoma and moving east, into eastern Oklahoma and western Arkansas, bringing the threat of heavy rain, gusty winds, and tornadoes.
Severe thunderstorm warnings were posted early on March 19 in Oklahoma, Kansas and Texas. Oklahoma also has a flash flood warning centered on Oklahoma City. Texas had a tornado warning near Midland earlier in the day.
The National Weather Service issued warnings today, March 19, 2012 for eastern Oklahoma and western Arkansas which stated
"Dangerous/potentially life-threatening flooding is expected." Forecasters at the National Weather Service expect 4 to 8 inch rainfall totals through Wednesday, March 21, and possibly moderate and major river flooding. For more information on the warnings, visit: http://www.srh.noaa.gov/tsa/dsp/dsp.php. For the audio version of the National Weather Service forecast for eastern Oklahoma and northwestern Arkansas, visit: http://www.srh.noaa.gov/images/rtimages/tsa/crs/mp3/OKCHAZARD.mp3.
Edward Olsen of NASA's Jet Propulsion Laboratory in Pasadena, Calif. creates imagery using data from the Atmospheric Infrared Sounder (AIRS) instrument that flies onboard NASA's Aqua satellite. Olsen created imagery from a satellite overpass during the morning hours today, March 19. He said, "The infrared and microwave images show the early phase of the convection blow-up."
A movie was created using infrared and visible data from NOAA's GOES-13 satellite from March 17 to March 19 at 1740 UTC (1:40 p.m. EST). When the AIRS data was matched with the GOES satellite animation, the blow-up of convection (rising air that forms thunderstorms) appears to have begun around 0245 UTC on March 19 (10:45 p.m. EST on March 18). In the satellite movie, the strong front comes together and resembles an upside-down arrow at the end of the animation on March 19.
GOES-13 is operated by the National Oceanic and Atmospheric Administration and the movie was created by NASA's GOES Project, located at NASA's Goddard Space Flight Center, Greenbelt, Md.
"The line on the Eastern edge of the active region is well established by the time of the AIRS overpass images (at 0853 UTC on March 19)," Olsen said. In the AIRS infrared image, strong convection (strongest on the eastern/leading edge) and cold cloud tops extend from Midland, Texas over the Texas Panhandle and Western Oklahoma and Kansas. The AIRS infrared image on March 19 at 0853 UTC (4:53 a.m. EST) showed cloud top were colder than -63F/-52.7C, indicating strong, high thunderstorm cloud tops that reached high up into the troposphere.
The NASA microwave imagery showed that the strongest convection and likely heavy precipitation was taking place in Oklahoma, just to the east of the Texas/Oklahoma border North of where I-40 crosses that border.
Severe weather is expected in that part of the country over the next couple of days and NASA and NOAA satellites continue to provide forecasters with valuable data.
###
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Infrared NASA satellite data indicates severe weather for south central US this weekPublic release date: 19-Mar-2012 [ | E-mail | Share ]
Contact: Rob Gutro Robert.j.gutro@nasa.gov 443-858-1779 NASA/Goddard Space Flight Center
Infrared and microwave satellite imagery from NASA have been providing forecasters at the National Weather Service valuable data on weather system that has potential to bring severe weather to the south central U.S. over the next several days.
A large upper-level storm system is approaching central Oklahoma and moving east, into eastern Oklahoma and western Arkansas, bringing the threat of heavy rain, gusty winds, and tornadoes.
Severe thunderstorm warnings were posted early on March 19 in Oklahoma, Kansas and Texas. Oklahoma also has a flash flood warning centered on Oklahoma City. Texas had a tornado warning near Midland earlier in the day.
The National Weather Service issued warnings today, March 19, 2012 for eastern Oklahoma and western Arkansas which stated
"Dangerous/potentially life-threatening flooding is expected." Forecasters at the National Weather Service expect 4 to 8 inch rainfall totals through Wednesday, March 21, and possibly moderate and major river flooding. For more information on the warnings, visit: http://www.srh.noaa.gov/tsa/dsp/dsp.php. For the audio version of the National Weather Service forecast for eastern Oklahoma and northwestern Arkansas, visit: http://www.srh.noaa.gov/images/rtimages/tsa/crs/mp3/OKCHAZARD.mp3.
Edward Olsen of NASA's Jet Propulsion Laboratory in Pasadena, Calif. creates imagery using data from the Atmospheric Infrared Sounder (AIRS) instrument that flies onboard NASA's Aqua satellite. Olsen created imagery from a satellite overpass during the morning hours today, March 19. He said, "The infrared and microwave images show the early phase of the convection blow-up."
A movie was created using infrared and visible data from NOAA's GOES-13 satellite from March 17 to March 19 at 1740 UTC (1:40 p.m. EST). When the AIRS data was matched with the GOES satellite animation, the blow-up of convection (rising air that forms thunderstorms) appears to have begun around 0245 UTC on March 19 (10:45 p.m. EST on March 18). In the satellite movie, the strong front comes together and resembles an upside-down arrow at the end of the animation on March 19.
GOES-13 is operated by the National Oceanic and Atmospheric Administration and the movie was created by NASA's GOES Project, located at NASA's Goddard Space Flight Center, Greenbelt, Md.
"The line on the Eastern edge of the active region is well established by the time of the AIRS overpass images (at 0853 UTC on March 19)," Olsen said. In the AIRS infrared image, strong convection (strongest on the eastern/leading edge) and cold cloud tops extend from Midland, Texas over the Texas Panhandle and Western Oklahoma and Kansas. The AIRS infrared image on March 19 at 0853 UTC (4:53 a.m. EST) showed cloud top were colder than -63F/-52.7C, indicating strong, high thunderstorm cloud tops that reached high up into the troposphere.
The NASA microwave imagery showed that the strongest convection and likely heavy precipitation was taking place in Oklahoma, just to the east of the Texas/Oklahoma border North of where I-40 crosses that border.
Severe weather is expected in that part of the country over the next couple of days and NASA and NOAA satellites continue to provide forecasters with valuable data.
###
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?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
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Public release date: 15-Jun-2012
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Holidays such as Memorial Day, 4th of July, Labor Day, or any picnic holiday can cause break downs in our otherwise healthy eating plan.? It is extremely important to be very aware that picnics can pack literally thousands of calories that we would not normally indulge in.? So, what should you do?
