Friday, June 29, 2012

Out of the Box Games Sponsor Review - Year of Jubilee Reviews

I love board games and get so excited to find fun yet educational games for the whole family. They have party games, engaging games, young player games. A game for everyone! Put away the video games and get out a great board game for the whole family.


I loved the idea of learning geography through a board game so I chose 10 Days in the Americas for my review game.?


2 of my boys played the first round alone, it was fun to watch them search for the route they needed to take to make their trip complete. The object of the game is to create a 10 day trip where each country is assessable to the one beside it on the individual's tray. The countries can either be next to each other or you would need to travel on a boat or airplane. By trading and exchanging cards you develop your 10 day trip in hops of being the first one done.?

I joined in with them for the next game. Sounded like it would be a piece of cake.. wrong! Just when you think you have a good sequence going you have to switch things around to get to the country at the end of your tray. It was great fun while I played with my 3 teen boys. I didn't win but I sure had fun trying! There were countries in the game I had never heard of and had to locate. Perfect for learning about new countries! I love that there are other 10 days games from Out of the Box, Africa, Europe, Asia and even the USA. A super fun way to learn geography as well as planning and thinking ahead in a game. Definitely takes some skill in decision making, ages 10 to adult.?

The game takes roughly 30 minutes to play, so not as involved as some all day long games. Super for a game night with the family or the middle of the homeschool day.?

You will be able to enter to win this game during the Luck of Liberty Blog Hop beginning July 2nd!

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Out of the Box Games Facebook?
@otbgames

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Disclosure: The reviews and or opinions on this blog are my own opinions. I received the above to review. No monitory compensation was received. I was not required to write a positive review. Your experience may differ. The opinions I have expressed are my own I am disclosing this in accordance with the Federal Trade Commissions 16 CFR Part 255: Guides Concerning the Use of Endorsement and Testimonials in Advertising.

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Thursday, June 28, 2012

Chicago SEO Online Marketing | Tradisionalindo

Chicago is home to a good successful digital marketplace, like online promotion, advertisements, flick era, web development as well as web marketing. Because from the mind-boggling want to form route within the business, Chicago Internet marketing has become a primary provider supplied throughout the majority of a digital businesses from the area. The most recent [...]

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Chicago SEO Online Marketing

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Chicago is home to a good successful digital marketplace, like online promotion, advertisements, flick era, web development as well as web marketing. Because from the mind-boggling want to form route within the business, Chicago Internet marketing has become a primary provider supplied throughout the majority of a digital businesses from the area. The most recent and a lot necessary traits inside...

Chicago is home to a good successful digital marketplace, like online promotion, advertisements, flick era, web development as well as web marketing. Because from the mind-boggling want to form route within the business, Chicago Internet marketing has become a primary provider supplied throughout the majority of a digital businesses from the area.
The most recent and a lot necessary traits inside the digital culture will be search engine marketing (Search engine marketing techniques). SEM is a type of Internet affiliate marketing that will wishes to produce internet websites by simply boosting ones own visibility from search website outcome webpages using compensated setting promoting, contextual marketing and advertising along with paid back development. Nevertheless, you cannot believe all styles of Online marketing need transaction, which is the reason Chicago marketing agencies own studied and also shared search engine optimization (Search engine marketing tactics).

Search engine optimization is the process pertaining to helping the rankings of the web page searching search engines via the ?natural? (un-paid) search engine results. The best end goal may be the greater and also earlier on the actual page plus much more often an affiliate site shows up inside serp?s number, the harder website visitors it?s going to obtain on the investigation engine?s purchasers. Chicago SEO firms currently have focused a variety of lookup, together with impact search, regional online research, video recording research, educative seek, news thumb investigation in addition to industry-specific look for.

A multitude of systems offers evolved all over the growth of online marketing in Chicago, il. In the event you try to get larger ratings for one?s company?s web-site, it is vital to obtain a Chicago SEO consultant for you to initial assist you understand how yahoo and google perform, which include what individuals try to look for, the actual search engine terms tapped out within search engines like google plus which in turn google usually are loved by its specific visitors. Once people figure out how google works, you can discover ways to make use of it is actually functionalities with the best desires.

Usually, Chi town web layout firms start out coordinating web pages with a practice referred to as market research. Keyword investigation requires getting precise search engine terms users enter into the various search engines whilst conducting a specialized look for. This sort of homework also unveils precisely how intense those people words are on the list of Online and in what way they are often ?searched? worldwide and in your location. After your Detroit SEO experts pick which keyword phrases to per website within your website, they start croping and enhancing the content and Html page document and connected coding to boost his or her significance for the unique keywords and phrases and eradicate barriers to the indexing actions involving engines like google.

Another SEO means of which many Chicago marketing agencies employ is the process of growing the amount of one way hyperlinks, or even backlinks, in the direction of your web page. This method is really as simple whenever publishing an unique squeeze page to the standard or even market pertinent directory site or even syndication website, hence creating a world wide web with links that adds to the position of this webpage. Particular Chicago local seo can really encourage you to definitely create a web site along with exceptional content, so you can besides send in your website, but your site, raising customer fascination in addition to assisting to put together a web business.

For more information about Chicago local seo visit our website.

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Friday, June 22, 2012

Richard's Real Estate and Urban Economics Blog: The problem with ...

Richard Green is a professor in the Sol Price School of Public Policy and the Marshall School of Business at the University of Southern California. This blog will feature commentary on the current state of housing, commercial real estate, mortgage finance, and urban development around the world. It may also at times have ruminations about graduate business education.

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Tuesday, June 19, 2012

MAYOR LEE LAUNCHES U.S. MAYORS OPEN GOVERNMENT INNOVATION PARTNERSHIP

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MAYOR LEE LAUNCHES U.S. MAYORS OPEN GOVERNMENT INNOVATION PARTNERSHIP

18 June 2012

Mayor Lee Joins the White House to Urge Mayors Across the Nation to Pledge

Innovation-Led Drive for Job Growth, Improved Government Efficiency & Greater Collaboration

Today, Mayor Edwin M. Lee, as Chair of the first U.S. Conference of Mayors (USCM) Technology and Innovation Task Force, announced the Open Government Innovation Partnership ? a call to action to help cities advance and prioritize innovation to drive job growth, economic development, improved efficiency and collaboration. The USCM Technology and Innovation Task Force will be asking Mayors to join the partnership as active and committed partners to help build an ecosystem that will help cities advance and prioritize innovation to improve government.

?This is a time for cities to confront challenges by taking risks and embracing innovation,? said Mayor Lee. ?In San Francisco, we are using technology and innovation to improve city services that impact our everyday lives, from transportation to education to civic engagement.?

The USCM Open Government Innovation Partnership will:
? Strengthen and increase civic use of innovation, cross-collaboration and improved accountability through open government initiatives;
? Showcase the leadership of cities highlighting innovation and creative best practices to increase opportunities for collaboration with the private sector;
? Secure commitments that will make city governments more efficient, effective, and responsive by embracing the use of open government innovation; and
? Empower private sector organizations to partner with government to make services more efficient, effective, and responsive to residents.

The action plans promote transparency, support a marketplace for entrepreneurship, energize civic engagement and collaboration, and leverage new technologies.

Last week, Mayor Lee hosted a forum recognizing the critical role that technology and innovation play in cities by sharing best practices to enable innovation at the 80th Annual Meeting of the U.S. Conference of Mayors in Orlando, Florida. The forum included former White House Chief Technology Officer Aneesh Chopra, White House Deputy Chief Technology Officer and former San Francisco Chief Information Officer Chris Vein and Code for America Executive Director Jen Pahlka.

The USCM Technology and Innovation Task Force also passed a resolution to support open government and the release of data at all levels of government to spur entrepreneurship, foster economic growth and create jobs. The mayors resolved to work closely with Congress and the Obama Administration to expand funding to support initiatives that direct resources to harness the capability of local economies nationwide in developing regional industry, innovation and export clusters.

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Saturday, June 16, 2012

Genetic markers hope for new brain tumor treatments

Genetic markers hope for new brain tumor treatments [ Back to EurekAlert! ] Public release date: 15-Jun-2012
[ | E-mail | Share Share ]

Contact: Emma Thorne
emma.thorne@nottingham.ac.uk
44-011-595-15793
University of Nottingham

Researchers at The University of Nottingham have identified three sets of genetic markers that could potentially pave the way for new diagnostic tools for a deadly type of brain tumour that mainly targets children.

The study, published in the latest edition of the prestigious journal 'Lancet Oncology, was led by Professor Richard Grundy at the University's Children's Brain Tumour Research Centre and Dr Suzanne Miller, a post doctoral research fellow in the Centre.

It focuses on a rare and aggressive cancer called Central Nervous System primitive neuro-ectodermal brain tumours. Patients with CNS PNET have a very poor prognosis and current treatments, including high dose chemotherapy and cranio-spinal radiotherapy are relatively unsuccessful and have severe lifelong side-effects. This is particularly the case in very young children.

Despite the need for new and more effective treatments, little research has been done to examine the underlying causes of CNS PNET, partly due to their rarity. The Nottingham study aimed to identify molecular markers as a first step to improving the treatments and therapies available to fight the cancer.

The Nottingham team collaborated with researchers at the Hospital for Sick Kids in Toronto, Canada, to perform an International study collecting 142 CNS PNET samples from 20 institutions in nine countries.

Professor Richard Grundy said: "Following our earlier research we realised that an international effort was needed to bring sufficient numbers of cases together to make the breakthrough we needed to better understand this disease or indeed diseases identified in our study. The next step is to translate this knowledge into improving treatments."

By studying the genetics of the tumours, they discovered that instead of one cancer, the tumours have three sub-types featuring distinct genetic abnormalities and leading to different outcomes for patients.

They found that each group had its own genetic signature through subtle differences in the way they expressed two genetic markers, LIN28 and OLIG2.

When compared with clinical factors including age, survival and metastases (the spread of the tumours through the body), they discovered that group 1 tumours (primitive neural) were found most often in the youngest patients and had the poorest survival rates. Patients with group 3 tumours had the highest incidence of metastases at diagnosis.

Ultimately, the research has identified the two genetic markers LIN28 and OLIG2 as a promising basis for more effective tools for diagnosing and predicting outcomes for young patients with these types of brain tumours.

The research was funded by the Canadian Institute of Health Research, the Brainchild/Sick Kids Foundation and the Samantha Dickson Brain Tumour Trust.

Chief Executive of Samantha Dickson Brain Tumour Trust, Sarah Lindsell, said: "As the UK's leading brain tumour charity, and the largest dedicated funder of brain tumour research, we are delighted that our investment has led to such significant success. It is great to see that understanding of these tumours is improving this is desperately needed given the poor outcomes for children with this tumour. Samantha Dickson Brain Tumour Trust is proud to have been instrumental in this work."

###

The Children's Brain Tumour Research Centre is one of the projects set to benefit from the Impact Campaign, the biggest fundraising campaign in The University of Nottingham's 130 year history. It aims to raise 150m to transform research, enrich the student experience and enable the institution to make an even greater contribution to the global communities it serves.

The paper, Markers of Survival and Metastatic Potential in Childhood CNS Primitive Neuro-Ectodermal Brain Tumours: an Integrative Genomic Analysis, can be accessed via The Lancet's website.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Genetic markers hope for new brain tumor treatments [ Back to EurekAlert! ] Public release date: 15-Jun-2012
[ | E-mail | Share Share ]

Contact: Emma Thorne
emma.thorne@nottingham.ac.uk
44-011-595-15793
University of Nottingham

Researchers at The University of Nottingham have identified three sets of genetic markers that could potentially pave the way for new diagnostic tools for a deadly type of brain tumour that mainly targets children.

The study, published in the latest edition of the prestigious journal 'Lancet Oncology, was led by Professor Richard Grundy at the University's Children's Brain Tumour Research Centre and Dr Suzanne Miller, a post doctoral research fellow in the Centre.

It focuses on a rare and aggressive cancer called Central Nervous System primitive neuro-ectodermal brain tumours. Patients with CNS PNET have a very poor prognosis and current treatments, including high dose chemotherapy and cranio-spinal radiotherapy are relatively unsuccessful and have severe lifelong side-effects. This is particularly the case in very young children.

Despite the need for new and more effective treatments, little research has been done to examine the underlying causes of CNS PNET, partly due to their rarity. The Nottingham study aimed to identify molecular markers as a first step to improving the treatments and therapies available to fight the cancer.

The Nottingham team collaborated with researchers at the Hospital for Sick Kids in Toronto, Canada, to perform an International study collecting 142 CNS PNET samples from 20 institutions in nine countries.

Professor Richard Grundy said: "Following our earlier research we realised that an international effort was needed to bring sufficient numbers of cases together to make the breakthrough we needed to better understand this disease or indeed diseases identified in our study. The next step is to translate this knowledge into improving treatments."

By studying the genetics of the tumours, they discovered that instead of one cancer, the tumours have three sub-types featuring distinct genetic abnormalities and leading to different outcomes for patients.

They found that each group had its own genetic signature through subtle differences in the way they expressed two genetic markers, LIN28 and OLIG2.

When compared with clinical factors including age, survival and metastases (the spread of the tumours through the body), they discovered that group 1 tumours (primitive neural) were found most often in the youngest patients and had the poorest survival rates. Patients with group 3 tumours had the highest incidence of metastases at diagnosis.

Ultimately, the research has identified the two genetic markers LIN28 and OLIG2 as a promising basis for more effective tools for diagnosing and predicting outcomes for young patients with these types of brain tumours.

The research was funded by the Canadian Institute of Health Research, the Brainchild/Sick Kids Foundation and the Samantha Dickson Brain Tumour Trust.

Chief Executive of Samantha Dickson Brain Tumour Trust, Sarah Lindsell, said: "As the UK's leading brain tumour charity, and the largest dedicated funder of brain tumour research, we are delighted that our investment has led to such significant success. It is great to see that understanding of these tumours is improving this is desperately needed given the poor outcomes for children with this tumour. Samantha Dickson Brain Tumour Trust is proud to have been instrumental in this work."

###

The Children's Brain Tumour Research Centre is one of the projects set to benefit from the Impact Campaign, the biggest fundraising campaign in The University of Nottingham's 130 year history. It aims to raise 150m to transform research, enrich the student experience and enable the institution to make an even greater contribution to the global communities it serves.

The paper, Markers of Survival and Metastatic Potential in Childhood CNS Primitive Neuro-Ectodermal Brain Tumours: an Integrative Genomic Analysis, can be accessed via The Lancet's website.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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